Day Spa Featuring Relaxation and Therapeutic Massage, Luxurious Facials featuring Pevonia Botanica Skincare products.

spa experience health and wellness center in siesta key logo 2
Spa & Wellness

The Science Behind CBD: How Cannabidiol Works in the Body?

June 7, 2023
woman holding the CBD treatment in siesta key 1

Are you looking to improve your health and well-being through CBD?

CBD, cannabidiol acid (CBDA), effectively treats inflammation, pain, anxiety, depression, and even specific issues related to cancer treatment. CBDA works primarily by interacting directly with the endocannabinoid system (ECS). The ECS consists of two types of receptors — cannabinoid 1 (CB1) and cannabinoid 2 (CB2) — located throughout various parts of the human body. When these receptors become activated, they can modify many physiological processes, including appetite control, mood regulation, stress response, and immune function.

As the interest in Cannabidiol (CBD) continues to grow, so does the need for a comprehensive understanding of how it works within the body. This article provides an overview of the science behind CBD and how its compounds interact with our systems.

Definition of Cannabidiol (CBD)

Cannabidiol, commonly known as CBD, is a compound derived from the Cannabis sativa species of plants. It is one of many cannabinoids found in hemp and marijuana plants. Unlike THC (tetrahydrocannabinol), which has psychoactive properties, CBD does not produce any mind-altering effects. As such, it has become increasingly popular for its potential therapeutic applications.

CBD works by interacting with the body’s endocannabinoid system—a network of receptors that help regulate mood, sleep, appetite, inflammation, and pain perception. The body produces its version of compounds called endocannabinoids; these bind to cannabinoid receptors throughout the brain and other body parts to trigger physiological responses. When taken orally or through inhalation, CBD stimulates those same receptors to produce similar effects without producing any intoxicating effects.

Endocannabinoid System In The Body

The endocannabinoid system is a complex network of receptors, neurotransmitters, and enzymes throughout the body. To understand the science behind CBD works in the body, it is essential first to understand this system. The endocannabinoid system consists of two types of cannabinoid receptors: CB1 and CB2. These receptors play a role in communication between cells, allowing them to interact with each other. They also regulate many physiological processes, such as appetite, pain perception, mood, and memory formation.

In addition to these endogenous (or naturally occurring) cannabinoids, there are also phytocannabinoids found in plants like hemp and cannabis, which can act on these same receptors in the body. One example of a plant-derived cannabinoid is cannabidiol (CBD). This compound acts as an agonist at both CB1 and CB2 receptors, binding to the receptor sites and stimulating their activity. By interacting with the endocannabinoid system through its cannabinoid agonists, CBD affects various aspects of human health, including reducing inflammation, improving sleep quality, relieving symptoms associated with anxiety or depression, and even helping reduce seizures in those with epilepsy.

Understanding the mechanisms behind this interaction will help researchers further explore the potential therapeutic benefits of CBD for treating medical conditions ranging from chronic pain to mental illnesses such as PTSD or OCD. As more studies uncover new information about how CBD interacts with our body’s natural functions via its interactions with our endocannabinoid systems, we can look forward to continued advances in understanding how best to use this powerful tool for promoting physical well-being and peace of mind

Effects of CBD on the Brain and Nervous System

CBD has been shown to have a direct influence on both the brain and nervous system. Research suggests CBD can help regulate key brain areas, including those involved in emotion processing, reward circuits, learning, and memory formation. In addition, CBD is thought to interact with neurotransmitter systems such as GABA-A and glutamate receptors for possible therapeutic effects on anxiety, seizures, pain perception, motor control, addiction behavior, and even depression.

Studies also suggest that CBD may be able to modulate the activity of various neural pathways within the brain by affecting serotonin levels. Moreover, recent evidence points towards the potential anti-inflammatory properties of CBD, which would account for its ability to reduce symptoms related to neurological disorders such as multiple sclerosis or epilepsy. It appears that these protective properties come from the interaction between cannabinoid receptors located in our immune cells and CB1 receptor stimulation within the brain itself; this could explain how CBD works as an effective neuroprotectant against diseases like Alzheimer’s disease or stroke damage.

Benefits of CBD on the Immune System

The endocannabinoid system, which is responsible for regulating body homeostasis and other functions, can be modulated by CBD. This modulation may have effects in boosting immunity and promoting better health outcomes through a variety of mechanisms.

The first mechanism is that CBD can activate specific receptors within the immune system to help fight off pathogens and regulate inflammation. It has also been shown to boost the activity of specific white blood cells involved in fighting infection and reduce inflammation-related cytokines. Additionally, research shows that CBD may help increase levels of substances like interleukins which are important for cell-mediated immunity and antibody production.

In addition to these direct immunological effects, there is evidence that CBD can indirectly improve immune function by reducing stress. Stress hormones such as cortisol suppress the immune system, while chronically elevated stress levels cause dysregulation in the immune response leading to increased susceptibility to infections or even autoimmune disorders. By reducing anxiety and improving sleep quality, CBD may help normalize cortisol levels, thereby protecting against some forms of illness caused by weakened immunity.

Potential Side Effects Of CBD

Despite the many potential health benefits of cannabidiol (CBD), it is essential to understand that some risks may be associated with its use. For one thing, CBD can interact with other medications, so patients need to discuss their usage with a qualified physician before trying any products containing this cannabinoid. Additionally, allergic reactions and adverse effects have been reported in those who take CBD-containing supplements or oils.

The most commonly reported side effects are drowsiness or fatigue. People should exercise caution when driving or operating dangerous machinery after taking CBD products. In addition, there have been reports of nausea and appetite changes in some users. As with any medication or supplement, individual results vary depending on dosage, frequency of use, and overall sensitivity to the compound and other ingredients included in the product formulation.

Regarding safety concerns regarding long-term use, research indicates that CBD is generally considered non-toxic even at high doses and does not pose an overdose risk for humans.

family walking together health and wellness center in siesta key 1

Delivery Methods For CBD

Cannabidiol (CBD) is available in many forms and through various delivery methods. CBD tinctures, edibles, topicals, vaping oils, and other products are all popular options for those wanting to incorporate them into their daily routine or as part of a specific treatment regimen.

The most common method to take CBD is orally via capsules or tablets. This ensures an exact dose is taken each time and delivers relief quickly after ingestion. Other oral solutions include tinctures containing alcohol-based extracts or oil-based liquid drops held under the tongue for up to 60 seconds before swallowing. Topical applications include creams and salves applied directly to areas experiencing discomfort.

Finally, more recent delivery systems involve inhalation via vape pens filled with pre-filled cartridges containing concentrated doses of cannabidiol isolate combined with flavored e-liquids. Vaping offers fast absorption while still allowing users control over dosage amounts. 


The science behind CBD offers a promising future for those struggling with many physical and psychological ailments. With its ability to interact with various systems in our body, it’s no wonder why so many are turning to this natural remedy. In addition, multiple delivery methods are available depending on your preference, including topical creams, tinctures, and edibles. So you should always consult your doctor before taking any new supplements.

At Spa Experience Siesta Key, we ensure all individuals receive safe access to life-changing holistic care to improve health and well-being. Contact us today.

You Might Also Like